Pachiderm
Our consortium aims to obtain key insights into the functions of L,D-peptidases, also called YkuD Domain peptidase or YDPases, in the bacterial envelope architecture. We defined four aims accordingly:
1) shedding light on the roles of LdtA, LdtB and LdtC in E. coli;
2) investigating the catalytic mechanisms of LD-peptidases;
3) exploring the role played by L,D-peptidases in bacterial predation;
4) investigate the function of L,D-peptidases and their role in the detachment of beta-barrels and the reticulation of PG in the pathogen B. abortus.
PAChiDERM - An ARC project from 1 October 2022 to 30 September 2027
Funded by the Federation Wallonie-Bruxelles (FWB), ARC projects are Concerted Research Action projects that aim at developing university or inter-university centres of excellence in fundamental research axes and, where possible, that carry out basic and applied research in an integrated manner and aim to make economic and social use of research results. They are awarded based on academic excellence of the applicants, the added value of each research group to achieve goals of research project, complementary skills of research teams and the methodology of proposed research program. They typically last for 4 to 5 years. In case of inter-university project, each team is financely supported by its own institution
